The accumulation of MMS-induced single strand breaks in G(1) phase is recombinogenic in DNA polymerase β defective mammalian cells

DNA polymerase (Pol) β null mouse embryonic fibroblasts provide a useful cell system to investigate the effects of alterations in base excision repair (BER) on genome stability. These cells are characterized by hypersensitivity to the cytotoxic effects of methyl methanesulfonate (MMS) and by decreas...

Täydet tiedot

Bibliografiset tiedot

Julkaisussa:	Nucleic Acids Res
Päätekijät:	Pascucci, Barbara, Russo, Maria Teresa, Crescenzi, Marco, Bignami, Margherita, Dogliotti, Eugenia
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Oxford University Press 2005
Aiheet:	Article
Linkit:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC546155/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15647510/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gki168
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