Human memory CD8 T cell effector potential is epigenetically preserved during in vivo homeostasis

Antigen-independent homeostasis of memory CD8 T cells is vital for sustaining long-lived T cell–mediated immunity. In this study, we report that maintenance of human memory CD8 T cell effector potential during in vitro and in vivo homeostatic proliferation is coupled to preservation of acquired DNA...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:J Exp Med
Main Authors: Abdelsamed, Hossam A., Moustaki, Ardiana, Fan, Yiping, Dogra, Pranay, Ghoneim, Hazem E., Zebley, Caitlin C., Triplett, Brandon M., Sekaly, Rafick-Pierre, Youngblood, Ben
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2017
Assuntos:
Research Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5461005/
https://ncbi.nlm.nih.gov/pubmed/28490440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20161760
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares