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11β-HSD1 Modulates the Set Point of Brown Adipose Tissue Response to Glucocorticoids in Male Mice

Glucocorticoids (GCs) are potent regulators of energy metabolism. Chronic GC exposure suppresses brown adipose tissue (BAT) thermogenic capacity in mice, with evidence for a similar effect in humans. Intracellular GC levels are regulated by 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) activity...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Endocrinology
मुख्य लेखकों: Doig, Craig L., Fletcher, Rachel S., Morgan, Stuart A., McCabe, Emma L., Larner, Dean P., Tomlinson, Jeremy W., Stewart, Paul M., Philp, Andrew, Lavery, Gareth G.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Endocrine Society 2017
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5460930/
https://ncbi.nlm.nih.gov/pubmed/28368470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2016-1722
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