Inhibition of 11β-HSD1 activity in vivo limits glucocorticoid exposure to human adipose tissue and decreases lipolysis

The pathophysiological importance of glucocorticoids (GC) is exemplified by patients with Cushing’s syndrome who develop hypertension, obesity and insulin resistance. At a cellular level, availability of GC to the glucocorticoid and mineralocorticoid receptors (GR and MR) is controlled by the isofor...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Clin Endocrinol Metab
Egile Nagusiak: Tomlinson, Jeremy W, Sherlock, Mark, Hughes, Beverley, Hughes, Susan V, Kilvington, Fiona, Bartlett, William, Courtney, Rachel, Rejto, Paul, Carley, William, Stewart, Paul M
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2007
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7611655/
https://ncbi.nlm.nih.gov/pubmed/17200165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2006-2325
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