טוען...
ANGPTL8 Blockade With a Monoclonal Antibody Promotes Triglyceride Clearance, Energy Expenditure, and Weight Loss in Mice
Angiopoietin-like protein (ANGPTL)8 is a negative regulator of lipoprotein lipase–mediated plasma triglyceride (TG) clearance. In this study, we describe a fully human monoclonal antibody (REGN3776) that binds monkey and human ANGPTL8 with high affinity. Inhibition of ANGPTL8 with REGN3776 in humani...
שמור ב:
| הוצא לאור ב: | Endocrinology |
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| Main Authors: | , , , , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Endocrine Society
2017
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5460832/ https://ncbi.nlm.nih.gov/pubmed/28204173 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2016-1894 |
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