Φορτώνει......
ANGPTL3 blockade with a human monoclonal antibody reduces plasma lipids in dyslipidemic mice and monkeys(1)
Angiopoietin-like protein 3 (ANGPTL3) is a circulating protein synthesized exclusively in the liver that inhibits LPL and endothelial lipase (EL), enzymes that hydrolyze TGs and phospholipids in plasma lipoproteins. Here we describe the development and testing of a fully human monoclonal antibody (R...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | J Lipid Res |
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| Κύριοι συγγραφείς: | , , , , , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
The American Society for Biochemistry and Molecular Biology
2015
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4479335/ https://ncbi.nlm.nih.gov/pubmed/25964512 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M054890 |
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