Glucocorticoids Induce Bone and Muscle Atrophy by Tissue-Specific Mechanisms Upstream of E3 Ubiquitin Ligases

Glucocorticoid excess, either endogenous with diseases of the adrenal gland, stress, or aging or when administered for immunosuppression, induces bone and muscle loss, leading to osteopenia and sarcopenia. Muscle weakness increases the propensity for falling, which, combined with the lower bone mass...

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Bibliografische gegevens
Gepubliceerd in:Endocrinology
Hoofdauteurs: Sato, Amy Y., Richardson, Danielle, Cregor, Meloney, Davis, Hannah M., Au, Ernie D., McAndrews, Kevin, Zimmers, Teresa A., Organ, Jason M., Peacock, Munro, Plotkin, Lilian I., Bellido, Teresita
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Endocrine Society 2017
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Research Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5460781/
https://ncbi.nlm.nih.gov/pubmed/28359087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2016-1779
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