Glucocorticoids Induce Bone and Muscle Atrophy by Tissue-Specific Mechanisms Upstream of E3 Ubiquitin Ligases

Glucocorticoid excess, either endogenous with diseases of the adrenal gland, stress, or aging or when administered for immunosuppression, induces bone and muscle loss, leading to osteopenia and sarcopenia. Muscle weakness increases the propensity for falling, which, combined with the lower bone mass...

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Detalhes bibliográficos
Publicado no:Endocrinology
Main Authors: Sato, Amy Y., Richardson, Danielle, Cregor, Meloney, Davis, Hannah M., Au, Ernie D., McAndrews, Kevin, Zimmers, Teresa A., Organ, Jason M., Peacock, Munro, Plotkin, Lilian I., Bellido, Teresita
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2017
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5460781/
https://ncbi.nlm.nih.gov/pubmed/28359087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2016-1779
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