Nrf2 regulates mass accrual and the antioxidant endogenous response in bone differently depending on the sex and age

Accumulation of reactive oxygen species (ROS) is an important pathogenic mechanism underling the loss of bone mass and strength with aging and other conditions leading to osteoporosis. The transcription factor erythroid 2-related factor2 (Nrf2) plays a central role in activating the cellular respons...

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Publicado en:PLoS One
Autores principales: Pellegrini, Gretel Gisela, Cregor, Meloney, McAndrews, Kevin, Morales, Cynthya Carolina, McCabe, Linda Doyle, McCabe, George P., Peacock, Munro, Burr, David, Weaver, Connie, Bellido, Teresita
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5289572/
https://ncbi.nlm.nih.gov/pubmed/28152064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0171161
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