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Lgr5 is a marker for fetal mammary stem cells, but is not essential for stem cell activity or tumorigenesis

The search for the bipotent mammary stem cells that drive mammary development requires markers to enable their prospective isolation. There is general agreement that bipotent mouse mammary stem cells are abundant in late fetal development, but their existence in the adult is vigorously debated. Amon...

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Publicat a:NPJ Breast Cancer
Autors principals: Trejo, Christy L., Luna, Gidsela, Dravis, Christopher, Spike, Benjamin T., Wahl, Geoffrey M.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5460261/
https://ncbi.nlm.nih.gov/pubmed/28649656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41523-017-0018-6
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