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Lgr5 is a marker for fetal mammary stem cells, but is not essential for stem cell activity or tumorigenesis

The search for the bipotent mammary stem cells that drive mammary development requires markers to enable their prospective isolation. There is general agreement that bipotent mouse mammary stem cells are abundant in late fetal development, but their existence in the adult is vigorously debated. Amon...

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Detalhes bibliográficos
Publicado no:NPJ Breast Cancer
Main Authors: Trejo, Christy L., Luna, Gidsela, Dravis, Christopher, Spike, Benjamin T., Wahl, Geoffrey M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5460261/
https://ncbi.nlm.nih.gov/pubmed/28649656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41523-017-0018-6
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