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Epigenetic and transcriptomic profiling of mammary gland development and tumor models disclose regulators of cell state plasticity
Cell state reprogramming during tumor progression complicates accurate diagnosis, compromises therapeutic effectiveness, and fuels metastatic dissemination. We used chromatin accessibility assays and transcriptional profiling during mammary development as an agnostic approach to identify factors tha...
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| Publicado no: | Cancer Cell |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6152943/ https://ncbi.nlm.nih.gov/pubmed/30174241 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2018.08.001 |
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