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Clonally stable Vκ allelic choice instructs Igκ repertoire
Although much has been done to understand how rearrangement of the Igκ locus is regulated during B-cell development, little is known about the way the variable (V) segments themselves are selected. Here we show, using B6/Cast hybrid pre-B-cell clones, that a limited number of V segments on each alle...
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| Izdano u: | Nat Commun |
|---|---|
| Glavni autori: | , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group
2017
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5459994/ https://ncbi.nlm.nih.gov/pubmed/28555639 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15575 |
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