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Differential accessibility at the κ chain locus plays a role in allelic exclusion

Gene rearrangement in the immune system is always preceded by DNA demethylation and increased chromatin accessibility. Using a model system in which rearrangement of the endogenous immunoglobulin κ locus is prevented, we demonstrate that these epigenetic and chromatin changes actually occur on one a...

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Sonraí Bibleagrafaíochta
Main Authors: Goldmit, Maya, Schlissel, Mark, Cedar, Howard, Bergman, Yehudit
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2002
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC129040/
https://ncbi.nlm.nih.gov/pubmed/12356741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf518
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