Differential accessibility at the κ chain locus plays a role in allelic exclusion

Gene rearrangement in the immune system is always preceded by DNA demethylation and increased chromatin accessibility. Using a model system in which rearrangement of the endogenous immunoglobulin κ locus is prevented, we demonstrate that these epigenetic and chromatin changes actually occur on one a...

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Detalles Bibliográficos

Publicado en:	EMBO J
Principais autores:	Goldmit, Maya, Schlissel, Mark, Cedar, Howard, Bergman, Yehudit
Formato:	Artigo
Idioma:	Inglês
Publicado:	Nature Publishing Group 2002
Assuntos:	Articles
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC129040/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12356741/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdf518
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