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A Novel Pax5-Binding Regulatory Element in the Igκ Locus

The Igκ locus undergoes a variety of different molecular processes during B cell development, including V(D)J rearrangement and somatic hypermutations (SHM), which are influenced by cis regulatory regions (RRs) within the locus. The Igκ locus includes three characterized RRs termed the intronic (iEκ...

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Detalhes bibliográficos
Main Authors: Levin-Klein, Rena, Kirillov, Andrei, Rosenbluh, Chaggai, Cedar, Howard, Bergman, Yehudit
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4033077/
https://ncbi.nlm.nih.gov/pubmed/24904588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2014.00240
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