The nuclear matrix protein CIZ1 facilitates localization of Xist RNA to the inactive X-chromosome territory

The nuclear matrix protein Cip1-interacting zinc finger protein 1 (CIZ1) promotes DNA replication in association with cyclins and has been linked to adult and pediatric cancers. Here we show that CIZ1 is highly enriched on the inactive X chromosome (Xi) in mouse and human female cells and is retaine...

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Publicado en:Genes Dev
Autores principales: Ridings-Figueroa, Rebeca, Stewart, Emma R., Nesterova, Tatyana B., Coker, Heather, Pintacuda, Greta, Godwin, Jonathan, Wilson, Rose, Haslam, Aidan, Lilley, Fred, Ruigrok, Renate, Bageghni, Sumia A., Albadrani, Ghadeer, Mansfield, William, Roulson, Jo-An, Brockdorff, Neil, Ainscough, Justin F.X., Coverley, Dawn
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5458755/
https://ncbi.nlm.nih.gov/pubmed/28546514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.295907.117
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