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Cardiomyocyte­-specific expression of the nuclear matrix protein, CIZ1, stimulates production of mono-nucleated cells with an extended window of proliferation in the postnatal mouse heart

Myocardial injury in mammals leads to heart failure through pathological cardiac remodelling that includes hypertrophy, fibrosis and ventricular dilatation. Central to this is inability of the mammalian cardiomyocyte to self-renew due to entering a quiescent state after birth. Modulation of the card...

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Dettagli Bibliografici
Pubblicato in:Biol Open
Autori principali: Bageghni, Sumia A., Frentzou, Georgia A., Drinkhill, Mark J., Mansfield, William, Coverley, Dawn, Ainscough, Justin F. X.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Company of Biologists Ltd 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5278428/
https://ncbi.nlm.nih.gov/pubmed/27934662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.021550
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