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Quantum chemical modeling of the reaction path of chorismate mutase based on the experimental substrate/product complex

Chorismate mutase is a well‐known model enzyme, catalyzing the Claisen rearrangement of chorismate to prephenate. Recent high‐resolution crystal structures along the reaction coordinate of this enzyme enabled computational analyses at unprecedented detail. Using quantum chemical simulations, we inve...

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Podrobná bibliografie
Vydáno v:FEBS Open Bio
Hlavní autoři: Burschowsky, Daniel, Krengel, Ute, Uggerud, Einar, Balcells, David
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5458464/
https://ncbi.nlm.nih.gov/pubmed/28593134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12224
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