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A novel noncovalent complex of chorismate mutase and DAHP synthase from Mycobacterium tuberculosis: protein purification, crystallization and X-ray diffraction analysis

Chorismate mutase catalyzes a key step in the shikimate-biosynthetic pathway and hence is an essential enzyme in bacteria, plants and fungi. Mycobacterium tuberculosis contains two chorismate mutases, a secreted and an intracellular one, the latter of which (MtCM; Rv0948c; 90 amino-acid residues; 10...

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Detalhes bibliográficos
Main Authors: Ökvist, Mats, Sasso, Severin, Roderer, Kathrin, Kast, Peter, Krengel, Ute
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765898/
https://ncbi.nlm.nih.gov/pubmed/19851019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309109035878
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