Human Fanconi anemia monoubiquitination pathway promotes homologous DNA repair

Fanconi anemia (FA) is a recessive disorder characterized by congenital abnormalities, progressive bone-marrow failure, and cancer susceptibility. Cells from FA patients are hypersensitive to agents that produce DNA crosslinks and, after treatment with these agents, have pronounced chromosome breaka...

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Bibliographic Details
Main Authors: Nakanishi, Koji, Yang, Yun-Gui, Pierce, Andrew J., Taniguchi, Toshiyasu, Digweed, Martin, D'Andrea, Alan D., Wang, Zhao-Qi, Jasin, Maria
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2005
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC545844/
https://ncbi.nlm.nih.gov/pubmed/15650050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0407796102
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