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Non-specific chemical inhibition of the Fanconi anemia pathway sensitizes cancer cells to cisplatin
BACKGROUND: Platinum compounds such as cisplatin and carboplatin are DNA crosslinking agents widely used for cancer chemotherapy. However, the effectiveness of platinum compounds is often tempered by the acquisition of cellular drug resistance. Until now, no pharmacological approach has successfully...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3478989/ https://ncbi.nlm.nih.gov/pubmed/22537224 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-11-26 |
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