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Discovery of novel heart rate-associated loci using the Exome Chip

Resting heart rate is a heritable trait, and an increase in heart rate is associated with increased mortality risk. Genome-wide association study analyses have found loci associated with resting heart rate, at the time of our study these loci explained 0.9% of the variation. This study aims to disco...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Hum Mol Genet
मुख्य लेखकों: van den Berg, Marten E., Warren, Helen R., Cabrera, Claudia P., Verweij, Niek, Mifsud, Borbala, Haessler, Jeffrey, Bihlmeyer, Nathan A., Fu, Yi-Ping, Weiss, Stefan, Lin, Henry J., Grarup, Niels, Li-Gao, Ruifang, Pistis, Giorgio, Shah, Nabi, Brody, Jennifer A., Müller-Nurasyid, Martina, Lin, Honghuang, Mei, Hao, Smith, Albert V., Lyytikäinen, Leo-Pekka, Hall, Leanne M., van Setten, Jessica, Trompet, Stella, Prins, Bram P., Isaacs, Aaron, Radmanesh, Farid, Marten, Jonathan, Entwistle, Aiman, Kors, Jan A., Silva, Claudia T., Alonso, Alvaro, Bis, Joshua C., de Boer, Rudolf, de Haan, Hugoline G., de Mutsert, Renée, Dedoussis, George, Dominiczak, Anna F., Doney, Alex S. F., Ellinor, Patrick T., Eppinga, Ruben N., Felix, Stephan B., Guo, Xiuqing, Hagemeijer, Yanick, Hansen, Torben, Harris, Tamara B., Heckbert, Susan R., Huang, Paul L., Hwang, Shih-Jen, Kähönen, Mika, Kanters, Jørgen K., Kolcic, Ivana, Launer, Lenore J., Li, Man, Yao, Jie, Linneberg, Allan, Liu, Simin, Macfarlane, Peter W., Mangino, Massimo, Morris, Andrew D., Mulas, Antonella, Murray, Alison D., Nelson, Christopher P., Orrú, Marco, Padmanabhan, Sandosh, Peters, Annette, Porteous, David J., Poulter, Neil, Psaty, Bruce M., Qi, Lihong, Raitakari, Olli T., Rivadeneira, Fernando, Roselli, Carolina, Rudan, Igor, Sattar, Naveed, Sever, Peter, Sinner, Moritz F., Soliman, Elsayed Z., Spector, Timothy D., Stanton, Alice V., Stirrups, Kathleen E., Taylor, Kent D., Tobin, Martin D., Uitterlinden, André, Vaartjes, Ilonca, Hoes, Arno W., van der Meer, Peter, Völker, Uwe, Waldenberger, Melanie, Xie, Zhijun, Zoledziewska, Magdalena, Tinker, Andrew, Polasek, Ozren, Rosand, Jonathan, Jamshidi, Yalda, van Duijn, Cornelia M., Zeggini, Eleftheria, Jukema, J. Wouter, Asselbergs, Folkert W., Samani, Nilesh J., Lehtimäki, Terho, Gudnason, Vilmundur, Wilson, James, Lubitz, Steven A., Kääb, Stefan, Sotoodehnia, Nona, Caulfield, Mark J., Palmer, Colin N. A., Sanna, Serena, Mook-Kanamori, Dennis O., Deloukas, Panos, Pedersen, Oluf, Rotter, Jerome I., Dörr, Marcus, O'Donnell, Chris J., Hayward, Caroline, Arking, Dan E., Kooperberg, Charles, van der Harst, Pim, Eijgelsheim, Mark, Stricker, Bruno H., Munroe, Patricia B.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Oxford University Press 2017
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5458336/
https://ncbi.nlm.nih.gov/pubmed/28379579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddx113
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