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Identification of small molecule inhibitors of the Aurora-A/TPX2 complex
Aurora kinases are a family of cell division regulators that govern the correct assembly of a bipolar mitotic spindle and the fidelity of chromosome segregation. Their overexpression is associated with genomic instability and aneuploidy, and is frequently observed in cancer. Accordingly, competitive...
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| 出版年: | Oncotarget |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Impact Journals LLC
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5458272/ https://ncbi.nlm.nih.gov/pubmed/28389630 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16738 |
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