Niclosamide is a potential therapeutic for familial adenomatosis polyposis by disrupting Axin-GSK3 interaction

The epithelial-mesenchymal transition (EMT) is implicated in tumorigenesis and cancer progression, and canonical Wnt signaling tightly controls Snail, a key transcriptional repressor of EMT. While the suppression of canonical Wnt signaling and EMT comprises an attractive therapeutic strategy, molecu...

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發表在:Oncotarget
Main Authors: Ahn, Sung Yong, Kim, Nam Hee, Lee, Kyungro, Cha, Yong Hoon, Yang, Ji Hye, Cha, So Young, Cho, Eunae Sandra, Lee, Yoonmi, Cha, Jeong Seok, Cho, Hyun Soo, Jeon, Yoon, Yuk, Young-Su, Cho, Suebean, No, Kyoung Tai, Kim, Hyun Sil, Lee, Ho, Choi, Jiwon, Yook, Jong In
格式: Artigo
語言:Inglês
出版: Impact Journals LLC 2017
主題:
Research Paper
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5458252/
https://ncbi.nlm.nih.gov/pubmed/28418862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16252
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