p53 regulates nuclear GSK-3 levels through miR-34-mediated Axin2 suppression in colorectal cancer cells

p53 is a bona fide tumor suppressor gene whose loss of function marks the most common genetic alteration in human malignancy. Although the causal link between loss of p53 function and tumorigenesis has been clearly demonstrated, the mechanistic links by which loss of p53 potentiates oncogenic signal...

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Библиографические подробности
Главные авторы: Kim, Nam Hee, Cha, Yong Hoon, Kang, Shi Eun, Lee, Yoonmi, Lee, Inhan, Cha, So Young, Ryu, Joo Kyung, Na, Jung Min, Park, Changbum, Yoon, Ho-Geun, Park, Gyeong-Ju, Yook, Jong In, Kim, Hyun Sil
Формат: Artigo
Язык:Inglês
Опубликовано: Landes Bioscience 2013
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Report
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3680537/
https://ncbi.nlm.nih.gov/pubmed/23624843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.24739
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