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Niclosamide is a potential therapeutic for familial adenomatosis polyposis by disrupting Axin-GSK3 interaction

The epithelial-mesenchymal transition (EMT) is implicated in tumorigenesis and cancer progression, and canonical Wnt signaling tightly controls Snail, a key transcriptional repressor of EMT. While the suppression of canonical Wnt signaling and EMT comprises an attractive therapeutic strategy, molecu...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Ahn, Sung Yong, Kim, Nam Hee, Lee, Kyungro, Cha, Yong Hoon, Yang, Ji Hye, Cha, So Young, Cho, Eunae Sandra, Lee, Yoonmi, Cha, Jeong Seok, Cho, Hyun Soo, Jeon, Yoon, Yuk, Young-Su, Cho, Suebean, No, Kyoung Tai, Kim, Hyun Sil, Lee, Ho, Choi, Jiwon, Yook, Jong In
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5458252/
https://ncbi.nlm.nih.gov/pubmed/28418862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16252
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