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Simple peptides derived from the ribosomal core potentiate RNA polymerase ribozyme function

The emergence of functional interactions between nucleic acids and polypeptides was a key transition in the origin of life and remains at the heart of all biology. However, how and why simple non-coded peptides could have become critical for RNA function is unclear. Here we show that putative ancien...

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Publicado en:Nat Chem
Main Authors: Tagami, Shunsuke, Attwater, James, Holliger, Philipp
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5458135/
https://ncbi.nlm.nih.gov/pubmed/28338682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchem.2739
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