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Ribozyme-catalysed RNA synthesis using triplet building blocks

RNA-catalyzed RNA replication is widely believed to have supported a primordial biology. However, RNA catalysis is dependent upon RNA folding, and this yields structures that can block replication of such RNAs. To address this apparent paradox, we have re-examined the building blocks used for RNA re...

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Détails bibliographiques
Publié dans:eLife
Auteurs principaux: Attwater, James, Raguram, Aditya, Morgunov, Alexey S, Gianni, Edoardo, Holliger, Philipp
Format: Artigo
Langue:Inglês
Publié: eLife Sciences Publications, Ltd 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6003772/
https://ncbi.nlm.nih.gov/pubmed/29759114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.35255
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