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The synthesis of blocked triplet-phosphoramidites and their use in mutagenesis.

A general approach for the synthesis of oligonucleotide-triplet phosphoramidites and the synthesis of four such blocks are described. A strategy was devised to minimize the number of dimer precursors needed for synthesis of a complete set of triplet-amidite blocks encoding all 20 amino acids. Wherea...

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Detalhes bibliográficos
Main Authors: Ono, A, Matsuda, A, Zhao, J, Santi, D V
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC307443/
https://ncbi.nlm.nih.gov/pubmed/8524660
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