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The synthesis of blocked triplet-phosphoramidites and their use in mutagenesis.
A general approach for the synthesis of oligonucleotide-triplet phosphoramidites and the synthesis of four such blocks are described. A strategy was devised to minimize the number of dimer precursors needed for synthesis of a complete set of triplet-amidite blocks encoding all 20 amino acids. Wherea...
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| Main Authors: | , , , |
|---|---|
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
1995
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| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC307443/ https://ncbi.nlm.nih.gov/pubmed/8524660 |
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