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In-ice evolution of RNA polymerase ribozyme activity

Mechanisms of molecular self-replication have the potential to shed light upon the origins of life. In particular, self-replication through RNA-catalysed templated RNA synthesis is thought to have supported a primordial ‘RNA World’. However, existing polymerase ribozymes lack the capacity to synthes...

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Detalhes bibliográficos
Main Authors: Attwater, James, Wochner, Aniela, Holliger, Philipp
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3920166/
https://ncbi.nlm.nih.gov/pubmed/24256864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchem.1781
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