Tyrosine phosphatase SHP-2 is a mediator of activity-dependent neuronal excitotoxicity

Calcium influx can promote neuronal differentiation and survival, at least in part by activating Ras and its downstream targets, including the Erk pathway. However, excessive calcium influx can initiate molecular signals leading to neuronal death during excitotoxicity or in neurodegenerative disease...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:EMBO J
Main Authors: Rusanescu, Gabriel, Yang, Wentian, Bai, Ailin, Neel, Benjamin G, Feig, Larry A
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2005
Fag:
Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC545812/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15650750/
https://ncbi.nlm.nih.govhttps://doi.org/10.1038/sj.emboj.7600522
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker