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Global mapping of CARM1 substrates defines enzyme specificity and substrate recognition
Protein arginine methyltransferases (PRMTs) introduce arginine methylation, a post-translational modification with the increasingly eminent role in normal physiology and disease. PRMT4 or coactivator-associated arginine methyltransferase 1 (CARM1) is a propitious target for cancer therapy; however,...
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| Published in: | Nat Commun |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Nature Publishing Group
2017
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5458078/ https://ncbi.nlm.nih.gov/pubmed/28537268 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms15571 |
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