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Global Phosphoproteome Analysis Using FAIMS on a Hybrid Orbitrap Mass Spectrometer

Mass spectrometry is the premier tool for identifying and quantifying protein phosphorylation on a global scale. Analysis of phosphopeptides requires enrichment, and even after the samples remain highly complex and exhibit broad dynamic range of abundance. Achieving maximal depth of coverage for pho...

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Detalles Bibliográficos
Publicado en:Anal Chem
Main Authors: Muehlbauer, Laura K., Hebert, Alexander S., Westphall, Michael S., Shishkova, Evgenia, Coon, Joshua J.
Formato: Artigo
Idioma:Inglês
Publicado: 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8051555/
https://ncbi.nlm.nih.gov/pubmed/33270415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.0c03415
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