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The Cytidine Deaminase APOBEC3 Family is Subject to Transcriptional Regulation by p53

The APOBEC3 (A3) family of proteins are DNA cytidine deaminases that act as sentinels in the innate immune response against retroviral infections and are responsive to interferon. Recently, a few A3 genes were identified as potent enzymatic sources of mutations in several human cancers. Using human...

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Vydáno v:Mol Cancer Res
Hlavní autoři: Menendez, Daniel, Nguyen, Thuy-Ai, Snipe, Joyce, Resnick, Michael A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5457717/
https://ncbi.nlm.nih.gov/pubmed/28232385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-17-0019
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