Pellino-1 promotes lung carcinogenesis via the stabilization of Slug and Snail through K63-mediated polyubiquitination

Pellino-1 is an E3 ubiquitin ligase acting as a critical mediator for a variety of immune receptor signaling pathways, including Toll-like receptors, interleukin-1 receptor and T-cell receptors. We recently showed that the Pellino-1-transgenic (Tg) mice developed multiple tumors with different subty...

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Veröffentlicht in:Cell Death Differ
Hauptverfasser: Jeon, Yoon Kyung, Kim, Chung Kwon, Hwang, Kyung Rim, Park, Hye-Young, Koh, Jaemoon, Chung, Doo Hyun, Lee, Chang-Woo, Ha, Geun-Hyoung
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2017
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Original Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5457685/
https://ncbi.nlm.nih.gov/pubmed/28009353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2016.143
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