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Pellino 1 promotes lymphomagenesis by deregulating BCL6 polyubiquitination
The signal-responsive E3 ubiquitin ligase pellino 1 (PELI1) regulates TLR and T cell receptor (TCR) signaling and contributes to the maintenance of autoimmunity; however, little is known about the consequence of mutations that result in upregulation of PELI1. Here, we developed transgenic mice that...
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Publicado no: | J Clin Invest |
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Main Authors: | , , , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Clinical Investigation
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4347227/ https://ncbi.nlm.nih.gov/pubmed/25295537 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI75667 |
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