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Pellino 1 promotes lymphomagenesis by deregulating BCL6 polyubiquitination
The signal-responsive E3 ubiquitin ligase pellino 1 (PELI1) regulates TLR and T cell receptor (TCR) signaling and contributes to the maintenance of autoimmunity; however, little is known about the consequence of mutations that result in upregulation of PELI1. Here, we developed transgenic mice that...
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| Yayımlandı: | J Clin Invest |
|---|---|
| Asıl Yazarlar: | , , , , , , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society for Clinical Investigation
2014
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4347227/ https://ncbi.nlm.nih.gov/pubmed/25295537 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI75667 |
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