Regulation of p63 Isoforms by Snail and Slug Transcription Factors in Human Squamous Cell Carcinoma

TP63 is a p53-related gene that contains two alternative promoters, which give rise to transcripts that encode proteins with (TAp63) or without (ΔNp63) an amino-transactivating domain. Whereas the expression of p63 is required for proper development of epithelial structures, the role of p63 in tumor...

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Detalhes bibliográficos
Main Authors: Herfs, Michael, Hubert, Pascale, Suarez-Carmona, Meggy, Reschner, Anca, Saussez, Sven, Berx, Geert, Savagner, Pierre, Boniver, Jacques, Delvenne, Philippe
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2010
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2843482/
https://ncbi.nlm.nih.gov/pubmed/20150431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090804
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