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Regulation of p63 Isoforms by Snail and Slug Transcription Factors in Human Squamous Cell Carcinoma
TP63 is a p53-related gene that contains two alternative promoters, which give rise to transcripts that encode proteins with (TAp63) or without (ΔNp63) an amino-transactivating domain. Whereas the expression of p63 is required for proper development of epithelial structures, the role of p63 in tumor...
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| Главные авторы: | , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Investigative Pathology
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2843482/ https://ncbi.nlm.nih.gov/pubmed/20150431 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090804 |
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