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Estimating TP53 Mutation Carrier Probability in Families with Li-Fraumeni Syndrome Using LFSPRO
BACKGROUND: Li-Fraumeni syndrome (LFS) is associated with germline TP53 mutations and a very high lifetime cancer risk. Algorithms that assess a patient's risk of inherited cancer predisposition are often used in clinical counseling. The existing LFS criteria have limitations, suggesting the ne...
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| Vydáno v: | Cancer Epidemiol Biomarkers Prev |
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| Hlavní autoři: | , , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2017
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5457344/ https://ncbi.nlm.nih.gov/pubmed/28137790 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-16-0695 |
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