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Reduced levels of Cacna1c attenuate mesolimbic dopamine system function

Genetic variation in CACNA1C, which codes for the L-type calcium channel (LTCC) Ca(v)1.2, is associated with clinical diagnoses of bipolar disorder, depression, and schizophrenia. Dysregulation of the mesolimbic dopamine (DA) system is linked to these syndromes and LTCCs are required for normal DAer...

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Bibliografiske detaljer
Udgivet i:Genes Brain Behav
Main Authors: Terrillion, Chantelle E., Dao, David T., Cachope, Roger, Lobo, Mary Kay, Puche, Adam C., Cheer, Joseph F., Gould, Todd D.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5457318/
https://ncbi.nlm.nih.gov/pubmed/28186690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/gbb.12371
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