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Reduced levels of Cacna1c attenuate mesolimbic dopamine system function

Genetic variation in CACNA1C, which codes for the L-type calcium channel (LTCC) Ca(v)1.2, is associated with clinical diagnoses of bipolar disorder, depression, and schizophrenia. Dysregulation of the mesolimbic dopamine (DA) system is linked to these syndromes and LTCCs are required for normal DAer...

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Détails bibliographiques
Publié dans:Genes Brain Behav
Auteurs principaux: Terrillion, Chantelle E., Dao, David T., Cachope, Roger, Lobo, Mary Kay, Puche, Adam C., Cheer, Joseph F., Gould, Todd D.
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5457318/
https://ncbi.nlm.nih.gov/pubmed/28186690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/gbb.12371
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