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Decreased Nucleus Accumbens Expression of Psychiatric Disorder Risk Gene Cacna1c Promotes Susceptibility to Social Stress
BACKGROUND: Polymorphisms in the CACNA1C gene are associated with human mood disorders. The rodent social defeat model of stress/mood-disorder susceptibility results in maladaptive consequences mediated by altered function of mesolimbic circuits. METHODS: mRNA levels of Cacna1c in the nucleus accumb...
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| Publicado no: | Int J Neuropsychopharmacol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5417061/ https://ncbi.nlm.nih.gov/pubmed/28165117 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ijnp/pyw112 |
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