Differential Effects of Polymorphic Alleles of FGF Receptor 4 on Colon Cancer Growth and Metastasis

A gly(388)arg polymorphism (rs351855) in the transmembrane domain of the fibroblast growth factor receptor (FGFR4) is associated with increased risk, staging, and metastasis in several different types of cancer. To specifically assess the impact of the polymorphic FGFR4 in colorectal cancer (CRC), w...

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Dettagli Bibliografici
Pubblicato in:Cancer Res
Autori principali: Heinzle, Christine, Gsur, Andrea, Hunjadi, Monika, Erdem, Zeynep, Gauglhofer, Christine, Stättner, Stefan, Karner, Josef, Klimpfinger, Martin, Wrba, Friedrich, Reti, Andrea, Hegedus, Balazs, Baierl, Andreas, Grasl-Kraupp, Bettina, Holzmann, Klaus, Grusch, Michael, Berger, Walter, Marian, Brigitte
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5455878/
https://ncbi.nlm.nih.gov/pubmed/22971346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-3654
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