Differential Effects of Polymorphic Alleles of FGF Receptor 4 on Colon Cancer Growth and Metastasis

A gly(388)arg polymorphism (rs351855) in the transmembrane domain of the fibroblast growth factor receptor (FGFR4) is associated with increased risk, staging, and metastasis in several different types of cancer. To specifically assess the impact of the polymorphic FGFR4 in colorectal cancer (CRC), w...

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Udgivet i:Cancer Res
Main Authors: Heinzle, Christine, Gsur, Andrea, Hunjadi, Monika, Erdem, Zeynep, Gauglhofer, Christine, Stättner, Stefan, Karner, Josef, Klimpfinger, Martin, Wrba, Friedrich, Reti, Andrea, Hegedus, Balazs, Baierl, Andreas, Grasl-Kraupp, Bettina, Holzmann, Klaus, Grusch, Michael, Berger, Walter, Marian, Brigitte
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5455878/
https://ncbi.nlm.nih.gov/pubmed/22971346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-3654
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