Differential Effects of Polymorphic Alleles of FGF Receptor 4 on Colon Cancer Growth and Metastasis

A gly(388)arg polymorphism (rs351855) in the transmembrane domain of the fibroblast growth factor receptor (FGFR4) is associated with increased risk, staging, and metastasis in several different types of cancer. To specifically assess the impact of the polymorphic FGFR4 in colorectal cancer (CRC), w...

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Gepubliceerd in:Cancer Res
Hoofdauteurs: Heinzle, Christine, Gsur, Andrea, Hunjadi, Monika, Erdem, Zeynep, Gauglhofer, Christine, Stättner, Stefan, Karner, Josef, Klimpfinger, Martin, Wrba, Friedrich, Reti, Andrea, Hegedus, Balazs, Baierl, Andreas, Grasl-Kraupp, Bettina, Holzmann, Klaus, Grusch, Michael, Berger, Walter, Marian, Brigitte
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5455878/
https://ncbi.nlm.nih.gov/pubmed/22971346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-3654
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