Differential Effects of Polymorphic Alleles of FGF Receptor 4 on Colon Cancer Growth and Metastasis

A gly(388)arg polymorphism (rs351855) in the transmembrane domain of the fibroblast growth factor receptor (FGFR4) is associated with increased risk, staging, and metastasis in several different types of cancer. To specifically assess the impact of the polymorphic FGFR4 in colorectal cancer (CRC), w...

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Détails bibliographiques
Publié dans:Cancer Res
Auteurs principaux: Heinzle, Christine, Gsur, Andrea, Hunjadi, Monika, Erdem, Zeynep, Gauglhofer, Christine, Stättner, Stefan, Karner, Josef, Klimpfinger, Martin, Wrba, Friedrich, Reti, Andrea, Hegedus, Balazs, Baierl, Andreas, Grasl-Kraupp, Bettina, Holzmann, Klaus, Grusch, Michael, Berger, Walter, Marian, Brigitte
Format: Artigo
Langue:Inglês
Publié: 2012
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5455878/
https://ncbi.nlm.nih.gov/pubmed/22971346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-3654
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