Differential Effects of Polymorphic Alleles of FGF Receptor 4 on Colon Cancer Growth and Metastasis

A gly(388)arg polymorphism (rs351855) in the transmembrane domain of the fibroblast growth factor receptor (FGFR4) is associated with increased risk, staging, and metastasis in several different types of cancer. To specifically assess the impact of the polymorphic FGFR4 in colorectal cancer (CRC), w...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Heinzle, Christine, Gsur, Andrea, Hunjadi, Monika, Erdem, Zeynep, Gauglhofer, Christine, Stättner, Stefan, Karner, Josef, Klimpfinger, Martin, Wrba, Friedrich, Reti, Andrea, Hegedus, Balazs, Baierl, Andreas, Grasl-Kraupp, Bettina, Holzmann, Klaus, Grusch, Michael, Berger, Walter, Marian, Brigitte
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5455878/
https://ncbi.nlm.nih.gov/pubmed/22971346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-3654
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