High Frequency and Poor Outcome of Philadelphia Chromosome–Like Acute Lymphoblastic Leukemia in Adults

PURPOSE: Philadelphia chromosome (Ph) –like acute lymphoblastic leukemia (ALL) is a high-risk subtype of childhood ALL characterized by kinase-activating alterations that are amenable to treatment with tyrosine kinase inhibitors. We sought to define the prevalence and genomic landscape of Ph-like AL...

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Publicat a:J Clin Oncol
Autors principals: Roberts, Kathryn G., Gu, Zhaohui, Payne-Turner, Debbie, McCastlain, Kelly, Harvey, Richard C., Chen, I-Ming, Pei, Deqing, Iacobucci, Ilaria, Valentine, Marcus, Pounds, Stanley B., Shi, Lei, Li, Yongjin, Zhang, Jinghui, Cheng, Cheng, Rambaldi, Alessandro, Tosi, Manuela, Spinelli, Orietta, Radich, Jerald P., Minden, Mark D., Rowe, Jacob M., Luger, Selina, Litzow, Mark R., Tallman, Martin S., Wiernik, Peter H., Bhatia, Ravi, Aldoss, Ibrahim, Kohlschmidt, Jessica, Mrózek, Krzysztof, Marcucci, Guido, Bloomfield, Clara D., Stock, Wendy, Kornblau, Stephen, Kantarjian, Hagop M., Konopleva, Marina, Paietta, Elisabeth, Willman, Cheryl L., Mullighan, Charles G.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Clinical Oncology 2017
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ORIGINAL REPORTS
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5455698/
https://ncbi.nlm.nih.gov/pubmed/27870571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2016.69.0073
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