Truncating erythropoietin receptor rearrangements in acute lymphoblastic leukemia

Chromosomal rearrangements are a hallmark of acute lymphoblastic leukemia (ALL) and are important ALL initiating events. We describe four different rearrangements of the erythropoietin receptor gene EPOR in Philadelphia chromosome-like (Ph-like) ALL. All of these rearrangements result in truncation...

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Detalhes bibliográficos
Publicado no:Cancer Cell
Main Authors: Iacobucci, Ilaria, Li, Yongjin, Roberts, Kathryn G., Dobson, Stephanie M., Kim, Jaeseung C., Payne-Turner, Debbie, Harvey, Richard C., Valentine, Marcus, McCastlain, Kelly, Easton, John, Yergeau, Donald, Janke, Laura J., Shao, Ying, Chen, I-Ming L., Rusch, Michael, Zandi, Sasan, Kornblau, Steven M., Konopleva, Marina, Jabbour, Elias, Paietta, Elisabeth M., Rowe, Jacob M., Pui, Ching-Hon, Gastier-Foster, Julie, Gu, Zhaohui, Reshmi, Shalini, Loh, Mignon L., Racevskis, Janis, Tallman, Martin S., Wiernik, Peter H., Litzow, Mark R., Willman, Cheryl L., McPherson, John D., Downing, James R., Zhang, Jinghui, Dick, John E., Hunger, Stephen P., Mullighan, Charles G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4750652/
https://ncbi.nlm.nih.gov/pubmed/26859458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2015.12.013
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