Truncating erythropoietin receptor rearrangements in acute lymphoblastic leukemia

Chromosomal rearrangements are a hallmark of acute lymphoblastic leukemia (ALL) and are important ALL initiating events. We describe four different rearrangements of the erythropoietin receptor gene EPOR in Philadelphia chromosome-like (Ph-like) ALL. All of these rearrangements result in truncation...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cancer Cell
Prif Awduron: Iacobucci, Ilaria, Li, Yongjin, Roberts, Kathryn G., Dobson, Stephanie M., Kim, Jaeseung C., Payne-Turner, Debbie, Harvey, Richard C., Valentine, Marcus, McCastlain, Kelly, Easton, John, Yergeau, Donald, Janke, Laura J., Shao, Ying, Chen, I-Ming L., Rusch, Michael, Zandi, Sasan, Kornblau, Steven M., Konopleva, Marina, Jabbour, Elias, Paietta, Elisabeth M., Rowe, Jacob M., Pui, Ching-Hon, Gastier-Foster, Julie, Gu, Zhaohui, Reshmi, Shalini, Loh, Mignon L., Racevskis, Janis, Tallman, Martin S., Wiernik, Peter H., Litzow, Mark R., Willman, Cheryl L., McPherson, John D., Downing, James R., Zhang, Jinghui, Dick, John E., Hunger, Stephen P., Mullighan, Charles G.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2016
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4750652/
https://ncbi.nlm.nih.gov/pubmed/26859458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2015.12.013
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