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Truncating erythropoietin receptor rearrangements in acute lymphoblastic leukemia

Chromosomal rearrangements are a hallmark of acute lymphoblastic leukemia (ALL) and are important ALL initiating events. We describe four different rearrangements of the erythropoietin receptor gene EPOR in Philadelphia chromosome-like (Ph-like) ALL. All of these rearrangements result in truncation...

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Bibliografski detalji
Izdano u:Cancer Cell
Glavni autori: Iacobucci, Ilaria, Li, Yongjin, Roberts, Kathryn G., Dobson, Stephanie M., Kim, Jaeseung C., Payne-Turner, Debbie, Harvey, Richard C., Valentine, Marcus, McCastlain, Kelly, Easton, John, Yergeau, Donald, Janke, Laura J., Shao, Ying, Chen, I-Ming L., Rusch, Michael, Zandi, Sasan, Kornblau, Steven M., Konopleva, Marina, Jabbour, Elias, Paietta, Elisabeth M., Rowe, Jacob M., Pui, Ching-Hon, Gastier-Foster, Julie, Gu, Zhaohui, Reshmi, Shalini, Loh, Mignon L., Racevskis, Janis, Tallman, Martin S., Wiernik, Peter H., Litzow, Mark R., Willman, Cheryl L., McPherson, John D., Downing, James R., Zhang, Jinghui, Dick, John E., Hunger, Stephen P., Mullighan, Charles G.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4750652/
https://ncbi.nlm.nih.gov/pubmed/26859458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2015.12.013
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